Coastal risk reduction features are often built to protect infrastructure and ecosystems from damaging waves, sea level rise, and shoreline erosion.Engineers often use predictive numerical modeling tools, such as Delft3D to help design optimal intervention strategies.Still, their use by coastal managers for optimizing the design of living shoreline
Does User Search Behaviour Mediate User Knowledge and Search Satisfaction?
Information searching in web environment is habitually tedious and challenging task.Rapid growth of web information HOLD MIST infrastructure has led to the rapid publication of information on web environment.Too many information publish on web cause information overload problem that preclude the success of information searching.Thus, reduce the sea
Role of Hepatic-Specific Transcription Factors and Polycomb Repressive Complex 2 during Induction of Fibroblasts to Hepatic Fate.
Direct reprogramming using defined sets of transcription factors (TFs) is a recent strategy for generating induced hepatocytes (iHeps) from fibroblasts for use in regenerative medicine and drug development.Comprehensive studies detailing the regulatory role of TFs during this reprogramming Cushion process could help increase its efficiency.This stu
UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
Summary: Colorectal cancer (CRC) is associated with metabolic and redox perturbation.The mitochondrial transporter uncoupling protein Lift Top Desk with Return 2 (UCP2) controls cell proliferation in vitro through the modulation of cellular metabolism, but the underlying mechanism in tumors in vivo remains unexplored.Using murine intestinal cancer
Lead/Drug Discovery from Natural Resources
Natural products and their derivatives have been shown to be effective drug candidates against various diseases for Changing Mat many years.Over a long period of time, nature has produced an abundant and prosperous source pool for novel therapeutic agents with distinctive structures.Major natural-product-based drugs approved for clinical use includ